产品货号：
Z17282
中文名称：
Filamin 1/FLNA抗体
英文名称：
Anti-Filamin 1/FLNA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Filamin 1/FLNA Antibody |
| 指标别名 | ABP 280;ABPX;Actin binding protein 280;Alpha filamin;DKFZp434P031;Filamin 1;Filamin A;FLN;FLN A;FLN1;FLNA;FMD;MNS;NHBP;Non muscle filamin;OPD;OPD1;OPD2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ICC/IF,ELISA |
| 基因名称 | FLNA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Filamin A/FLNA recombinant protein (Position:E451-Q638). |
| 实际分子量 | 281KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Filamin A,alpha (FLNA) is a protein that in humans is encoded by the FLNA gene.It is mapped to Xq28.The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins.The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration.This protein interacts with integrins,transmembrane receptor complexes,and second messengers.Defects in this gene are a cause of several syndromes,including periventricular nodular heterotopias (PVNH1,PVNH4),otopalatodigital syndromes (OPD1,OPD2),frontometaphyseal dysplasia (FMD),Melnick-Needles syndrome (MNS),and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX).Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | P21333 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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