产品货号：
Z17277
中文名称：
Gelsolin/GSN抗体
英文名称：
Anti-Gelsolin/GSN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Gelsolin/GSN Antibody |
| 指标别名 | Actin depolymerizing factor;ADF;AGEL;Brevin;Gelsolin;GSN |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM |
| 基因名称 | GSN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Gelsolin(763-775aa WDDDYWSVDPLDR),identical to the related rat sequence,and different from the related mouse sequence by one amino acid. |
| 实际分子量 | 86KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Gelsolin also known as GNS is an actin-binding protein that is a key regulator of actin filament assembly and disassembly.Gelsolin is one of the most potent members of the actin-severing gelsolin/villin superfamily.The gene was assigned to human chromosome 9q33.2.Gelsolin is also known as brevin,or actin-depolymerizing factor;it is the principal intracellular and extracellular actin-severing protein.Gelsolin and Gc protein together constitute the extracellular actin-scavenger system which prevents the toxic effects of actin release into the extracellular space under circumstances of cell necrosis.Gelsolin may have therapeutic potential as a mucolytic agent in CF patients.The antiapoptotic activity of gelsolin seems to prevent a step leading to cytochrome c release from the mitochondria into the cytosol. |
| Uniprot ID | P06396 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | gelsolin |
| 蛋白名全称 | Gelsolin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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