产品货号：
Z17270
中文名称：
Geminin/GMNN抗体
英文名称：
Anti-Geminin/GMNN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Geminin/GMNN Antibody |
| 指标别名 | Gem;Geminin;GMNN;RP3 369A17.3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | GMNN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Geminin/GMNN recombinant protein (Position:V21-E196). |
| 实际分子量 | 25KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Geminin,DNA replication inhibitor,also known as GMNN,is a protein in humans encoded by the GMNN gene.This gene encodes a protein that plays a critical role in cell cycle regulation.The encoded protein inhibits DNA replication by binding to DNA replication factor Cdt1,preventing the incorporation of minichromosome maintenance proteins into the pre-replication complex.The encoded protein is expressed during the S and G2 phases of the cell cycle and is degraded by the anaphase-promoting complex during the metaphase-anaphase transition.Increased expression of this gene may play a role in several malignancies including colon,rectal and breast cancer.Alternatively spliced transcript variants have been observed for this gene,and two pseudogenes of this gene are located on the short arm of chromosome 16. |
| Uniprot ID | O75496 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | geminin DNA replication inhibitor |
| 蛋白名全称 | Geminin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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