产品货号：
Z17236
中文名称：
GRIK4抗体
英文名称：
Anti-GRIK4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GRIK4 Antibody |
| 指标别名 | EAA1;GluK4;GRIK;Grik4;KA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | GRIK4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Grik4 antibody was raised against a 18 amino acid synthetic peptide near the carboxy terminus of the mouse Grik4.The immunogen is located within the last 50 amino acids of Grik4. |
| 计算分子量 | 107kDa |
| 成分 | Grik4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Grik4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Grik4 codes for the KA1 subunit of kainate-type ionotropic glutamate receptors which are critical regulators of network activity that act by modifying neuronal excitability,directly and indirectly,through GABAergic interneurons.Five subunits can assemble to form kainate receptors (KARs):GluR5 (coded by Grik1),GluR6 (coded by Grik2),and GluR7 (coded by Grik3) are the low-affinity subunits,and KA1 and KA2 are the high-affinity subunits.In the adult brain,KARs are located pre- and postsynaptically on pyramidal cells and on interneurons.Kainate receptors on GABA-containing interneurons enhance GABA release and thereby downregulate glutamatergic signaling.KARs have been implicated in numerous psychiatric disorders.Case control studies show significant association of Grik4 with both schizophrenia and bipolar disorder. |
| Uniprot ID | Q8BMF5 |
| 基因名全称 | Glutamate receptor,ionotropic,kainate 4 |
| 蛋白名全称 | Glutamate receptor,ionotropic,kainate 4 |
| 推荐稀释比 | Grik4 antibody can be used for detection of Grik4 by Western blot at 0.5 ～ 2μg/mL.Despite its predicted molecular weight,Grik4 often migrates at a lower molecular weight in SDS-PAGE.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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