产品货号：
Z17206
中文名称：
GLI3抗体
英文名称：
Anti-GLI3 Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GLI3 Antibody |
| 指标别名 | ACLS;GCPS;GLI family zinc finger 3;GLI3;PAP A;PAPA;PAPA1;PAPB;PHS;PPDIV;Zinc finger protein GLI3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,IF,ELISA |
| 基因名称 | GLI3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was produced from monospecific rabbit serum by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 30-60 of human Gli-3 protein. |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity-purified antibody is directed against human Gli-3 protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.?A BLAST analysis was used to suggest cross-reactivity with Gli-3 from human,chimpanzee,squirrel monkey,Xenopus laevis,chicken,dog and quail based on 100% sequence homology with the immunogen.Reactivity is also expected against homologues from mouse (94%) and rat (88%) based on partial homology.Reactivity with Gli-3 from other sources is not known. |
| 浓度 | 1.0mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers.Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal.Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues,including lung,colon,spleen,placenta,testis,and myometrium.Defects in Gli-3 are the cause of Greig cephalo-poly-syndactyly syndrome (GCPS);an autosomal dominant disorder-affecting limb and cranio-facial development.Two isoforms of human Gli-3 have been reported.One is the full-length protein at~170～190kDa and the other is a truncated isoform at~80kDa. |
| Uniprot ID | P10071 |
| 推荐稀释比 | Western blot (WB) 1:500 - 1:2,000 Immunohistochemistry 0.5mg/mL - 5μg/mL Other Dilution User Optimized |
相关搜索：GLI3抗体，GLI3多抗，Anti-GLI3 Antibody