产品货号:
Z17112
中文名称:
GPAT1/GPAM抗体
英文名称:
Anti-GPAT1/GPAM Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GPAT1/GPAM Antibody |
指标别名 | GPAT,GPAT1,KIAA1560,Glycerol-3-phosphate acyltransferase 1,mitochondrial,GPAT-1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | GPAM |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | GPAT1 antibody was raised against a 15 amino acid synthetic peptide near the carboxy terminus of the human GPAT1.The immunogen is located within amino acids 730 - 780 of GPAT1. |
计算分子量 | 94kDa |
成分 | GPAT1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | GPAT1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Glycerol-3-phosphate acyltransferase 1 (GPAT1),one of four known GPAT isoforms,is located on the mitochondrial outer membrane,allowing reciprocal regulation with carnitine palmitoyltransferase-1.It is thought to be critical for the development of hepatic steatosis;steatosis triggered by GPAT1 overexpression leads to hepatic and possibly peripheral insulin resistance.GPAT1 is transcriptionally upregulated by insulin and sterol regulatory element binding protein (SREBP-1) and downregulated by AMP-activated protein kinase.Mice deficient in GPAT1 exhibit decreased triacylglycerol (TAG) in cardiomyocytes even in high-fat diets,suggesting that GPAT1 contributes significantly to TAG accumulation in heart tissue during lipogenic or high fat diets. |
Uniprot ID | Q9HCL2 |
基因名全称 | Glycerol-3-phosphate acyltransferase,mitochondrial |
蛋白名全称 | Glycerol-3-phosphate acyltransferase,mitochondrial |
推荐稀释比 | GPAT1 antibody can be used for detection of GPAT1 by Western blot at 1 ~ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse and rat samples.All other applications and species not yet tested. |
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