产品货号：
Z17081
中文名称：
GFRA1抗体
英文名称：
Anti-GFRA1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GFRA1 Antibody |
| 指标别名 | Golgi-associated;gamma adaptin ear-containing;ARF-binding protein 1;Gga1;;GFRA1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC |
| 基因名称 | GFRA1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human GFRA1 recombinant protein (Position:D25-Q227).Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1. |
| 实际分子量 | 51KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | GDNF family receptor alpha-1 (GFRα1),also known as the GDNF receptor or GFRA1,is a protein that in humans is encoded by the GFRA1 gene.It is mapped to chromosome 10q25.3.The protein encoded by this gene is a member of the GDNF receptor family.GFRA1 is released by neuronal cells,Schwann cells,and injured sciatic nerve.It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN,and mediates activation of the RET tyrosine kinase receptor.This gene is also a candidate gene for Hirschsprung disease.Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase. |
| Uniprot ID | P56159 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | GDNF family receptor alpha 1 |
| 蛋白名全称 | GDNF family receptor alpha-1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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