产品货号:
Z16940
中文名称:
GDNF抗体
英文名称:
Anti-GDNF Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-GDNF Antibody |
指标别名 | glial cell derived neurotrophic factor;ATF;ATF1;ATF2;HFB1-GDNF;HSCR3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC |
基因名称 | GDNF |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | A synthetic peptide corresponding to a sequence in the middle region of human GDNF(142-158aa FRYCSGSCDAAETTYDK),different from the related mouse sequence by three amino acids and rat sequence by two amino acids. |
实际分子量 | 24KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | GDNF,Glial cell-derived neurotrophic factor,is a protein that,in humans,is encoded by the GDNF gene.GDNF is a small protein that potently promotes the survival of many types of neurons.GDNF is a founding member of the GDNF family of ligands(GFL).The GDNF gene is mapped to human chromosome 5p13.1-p12 by fluorescence in situ hybridization(FISH).This gene encodes a highly conserved neurotrophic factor.The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture,and was able to prevent apoptosisof motor neurons induced by axotomy.The encoded protein is processed to a mature secreted form that exists as a homodimer.The mature form of the protein is a ligand for the product of the RET(rearranged during transfection) protooncogene. |
Uniprot ID | P39905 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | glial cell derived neurotrophic factor |
蛋白名全称 | Glial cell line-derived neurotrophic factor(hGDNF) |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry(Paraffin-embedded Section) 1:50~400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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