产品货号：
Z16698
中文名称：
EVER1/TMC6抗体
英文名称：
Anti-EVER1/TMC6 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EVER1/TMC6 Antibody |
| 指标别名 | EV1,EVER1,EVIN1,LAK-4P,Transmembrane channel-like protein 6,Epidermodysplasia verruciformis protein 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | TMC6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | EVER1 antibody was raised against a 14 amino acid synthetic peptide from near the amino terminus of human EVER1.The immunogen is located within the first 50 amino acids of EVER1. |
| 计算分子量 | 90kDa |
| 成分 | EVER1 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | EVER1 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin.EV is caused by mutations in either of two adjacent genes,EVER1 and EVER2,located on chromosome 17q25.3.Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels.Both EVER1 and EVER2 are members of the transmembrane channel-like (TMC) protein family.EVER1 possesses eight trans-membrane domains and two leucine zipper motifs.EVER1 and EVER2 form a complex and interact with the zinc transporter 1 (ZnT-1),suggesting that EVER1 and EVER2 act to regulate cellular zinc balance. |
| Uniprot ID | Q7Z403 |
| 基因名全称 | Transmembrane channel-like 6 |
| 蛋白名全称 | Transmembrane channel-like 6 |
| 推荐稀释比 | EVER1 antibody can be used for the detection of EVER1 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in human samples.All other applications and species not yet tested. |
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