产品货号：
Z16695
中文名称：
EVI1/MECOM抗体
英文名称：
Anti-EVI1/MECOM Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EVI1/MECOM Antibody |
| 指标别名 | AML1 EVI 1;EVI 1;EVI1;MDS1 EVI1;MECOM;PRDM3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | MECOM |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human EVI1/MECOM recombinant protein (Position:E125-D743). |
| 实际分子量 | 138KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene.The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis,apoptosis,development,and cell differentiation and proliferation.The encoded protein can interact with CTBP1,SMAD3,CREBBP,KAT2B,MAPK8,and MAPK9.This gene can undergo translocation with the AML1 gene,resulting in overexpression of this gene and the onset of leukemia.Several transcript variants encoding a few different isoforms have been found for this gene. |
| Uniprot ID | Q03112 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | MDS1 and EVI1 complex locus |
| 蛋白名全称 | Histone-lysine N-methyltransferase MECOM |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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