FLASH/CASP8AP2抗体

产品货号：

Z16608

中文名称：

FLASH/CASP8AP2抗体

英文名称：

Anti-FLASH/CASP8AP2 Antibody

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-FLASH/CASP8AP2 Antibody
指标别名	CED-4,FLASH,RIP25,KIAA1315,CASP8-associated protein 2,FLICE-associated huge protein
克隆性	Polyclonal
检验物种	human
应用范围	ELISA,WB,ICC,IF
基因名称	CASP8AP2
抗体来源	Rabbit
抗体类型	IgG
免疫原	FLASH antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of human FLASH which differ from those of mouse by one amino acid.The immunogen is located within the last 50 amino acids of FLASH.
计算分子量	223kDa
成分	FLASH Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式	FLASH Antibody is affinity chromatography purified via peptide column.
浓度	1mg/mL
产品形态	溶液
保存条件	4℃可保存3个月，-20℃可保存1年。
背景资料	A novel mammalian CED-4 homologous was recently identified and cloned in mouse and human and designated FLASH (for FLICE-associated huge protein).FLASH is involved in Fas induced apoptosis.It is recruited to Fas after the receptor cross-linking.Overexpression of wild type of FLASH facilitates and its dominant negative form inhibits Fas induced apoptosis.FLASH interacts with the DEDs of caspase-8 and FADD through the DED-like domain of FLASH and mediates activation of caspase-8.There are parallels between FLASH and Apaf-1/CED-4 although there are arguments against their structural similarity.FLASH is widely expressed.
Uniprot ID	Q9UKL3
基因名全称	Caspase 8 associated protein 2
蛋白名全称	Caspase 8 associated protein 2
推荐稀释比	FLASH antibody can be used for detection of FLASH by Western blot at 0.5μg/mL.An approximate 220kDa band can be detected.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested.

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