产品货号:
Z16530
中文名称:
EVI1/MECOM抗体
英文名称:
Anti-EVI1/MECOM Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-EVI1/MECOM Antibody |
指标别名 | AML1 EVI 1;EVI 1;EVI1;MDS1 EVI1;MECOM;PRDM3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB,IHC,ELISA |
基因名称 | MECOM |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human PRDM3 |
计算分子量 | 138KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | MDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger protein 3 (PRDM3) is a protein that in humans is encoded by the MECOM gene.The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis,apoptosis,development,and cell differentiation and proliferation.The encoded protein can interact with CTBP1,SMAD3,CREBBP,KAT2B,MAPK8,and MAPK9.This gene can undergo translocation with the AML1 gene,resulting in overexpression of this gene and the onset of leukemia.Several transcript variants encoding a few different isoforms have been found for this gene. |
Uniprot ID | Q03112 |
基因名全称 | MDS1 and EVI1 complex locus protein |
蛋白名全称 | MDS1 and EVI1 complex locus protein |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 ELISA 1:20000 |
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