产品货号：
Z16527
中文名称：
EVL抗体
英文名称：
Anti-EVL Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-EVL Antibody |
| 指标别名 | Ena/VASP like protein,Enah/Vasp like,EVL,RNB6 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | EVL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human EVL recombinant protein (Position:M268-E400). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Ena/VASP-like protein is a member of the Ena/VASP family of proteins that in humans is encoded by the EVL gene.Ena/VASP-like (EVL) protein is a member of the Ena/VASP family and is involved in actin-associated cytoskeleton remodeling and cell polarity activities including axon guidance and lamellipodia formation in migrating cells.The EVL protein sequence contains an N-terminal EVH1 domain,a Pro-rich SH3 binding domain,and a C-terminal EVH2 domain.EVL domain interactions with G- and F-actin mediates actin nucleation and polymerization.Research studies have shown that EVL also regulates DNA repair by direct interaction with RAD51.EVL may function in the DSB repair pathway through the EVH2 domain,which possesses DNA-binding and RAD51 binding activity,thereby coordinating homologous DNA recombination.Research studies have shown EVL expression is up-regulated in human breast cancer associated with clinical stages and may be implicated in invasion and/or metastasis of human breast cancer. |
| Uniprot ID | Q9UI08 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | Enah/Vasp-like |
| 蛋白名全称 | Ena/VASP-like protein |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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