产品货号：
Z16432
中文名称：
GADD45B抗体
英文名称：
Anti-GADD45B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-GADD45B Antibody |
| 指标别名 | GADD45B;MYD118;Negative growth regulatory protein MyD118 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | GADD45B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of human GADD45B (EELLVAAQRQDRLTVGVYE). |
| 实际分子量 | 18KD |
| 成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Growth arrest and DNA-damage-inducible,beta,also known as GADD45B,is a protein which in humans is encoded by the GADD45B gene.This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents.The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway.This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase,which is an upstream activator of both p38 and JNK MAPKs.The function of these genes or their protein products is involved in the regulation of growth and apoptosis.These genes are regulated by different mechanisms,but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. |
| Uniprot ID | O75293 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | growth arrest and DNA damage inducible beta |
| 蛋白名全称 | Growth arrest and DNA damage-inducible protein GADD45 beta |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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