产品货号：
Z16004
中文名称：
DUSP6抗体
英文名称：
Anti-DUSP6 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DUSP6 Antibody |
| 指标别名 | Dual specificity protein phosphatase 6;DUSP6;HH19;MKP3;PYST1;MAP kinase phosphatase 3;MKP-3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF,FCM,ELISA |
| 基因名称 | DUSP6 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DUSP6 recombinant protein (Position:M1-T381). |
| 实际分子量 | 50KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK,SAPK/JNK,p38),which are associated with cellular proliferation and differentiation.Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases,different tissue distribution and subcellular localization,and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates ERK2,is expressed in a variety of tissues with the highest levels in heart and pancreas,and unlike most other members of this family,is localized in the cytoplasm.Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism.Alternatively spliced transcript variants have been found for this gene. |
| Uniprot ID | Q16828 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | dual specificity phosphatase 6 |
| 蛋白名全称 | Dual specificity protein phosphatase 6 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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