产品货号:
Z16003
中文名称:
DUSP6抗体
英文名称:
Anti-DUSP6 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DUSP6 Antibody |
指标别名 | Dual specificity protein phosphatase 6;DUSP6;HH19;MKP3;PYST1;MAP kinase phosphatase 3;MKP-3 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,IF,ELISA |
基因名称 | DUSP6 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human MKP-3 |
计算分子量 | 42KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Dual specificity phosphatase 6 (DUSP6) is an enzyme that in humans is encoded by the DUSP6 gene.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK,SAPK/JNK,p38),which are associated with cellular proliferation and differentiation.Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases,different tissue distribution and subcellular localization,and different modes of inducibility of their expression by extracellular stimuli.This gene product inactivates ERK2,is expressed in a variety of tissues with the highest levels in heart and pancreas,and unlike most other members of this family,is localized in the cytoplasm.Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism.Alternatively spliced transcript variants have been found for this gene. |
Uniprot ID | Q16828 |
基因名全称 | Dual specificity protein phosphatase 6 |
蛋白名全称 | Dual specificity protein phosphatase 6 |
推荐稀释比 | WB 1:500~1:2000 IHC 1:100~1:300 IF 1:200~1:1000 ELISA 1:20000 |
相关搜索:DUSP6抗体,DUSP6多抗,Anti-DUSP6 Antibody