产品货号：
Z15984
中文名称：
DUSP3抗体
英文名称：
Anti-DUSP3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DUSP3 Antibody |
| 指标别名 | dual specificity phosphatase 3;DUSP3;VHR |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,FCM,ELISA |
| 基因名称 | DUSP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DUSP3 recombinant protein (Position:S4-P185). |
| 实际分子量 | 20KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dual specificity protein phosphatase 3 is an enzyme that in humans is encoded by the DUSP3 gene.It is mapped to 17q21.31.The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK,SAPK/JNK,p38),which are associated with cellular proliferation and differentiation.Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases,different tissue distribution and subcellular localization,and different modes of inducibility of their expression by extracellular stimuli.This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer.Although DUSP3 is expressed in both breast and ovarian tissues,mutation screening in breast cancer pedigrees and in sporadic tumors was negative,leading to the conclusion that this gene is not BRCA1. |
| Uniprot ID | P51452 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | dual specificity phosphatase 3 |
| 蛋白名全称 | Dual specificity protein phosphatase 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry in fixed cells 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 |
相关搜索：DUSP3抗体，DUSP3多抗，Anti-DUSP3 Antibody