产品货号：
Z15979
中文名称：
DSG3抗体
英文名称：
Anti-DSG3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DSG3 Antibody |
| 指标别名 | Desmoglein-3;CDHF6;DSG3;PVA;Cadherin family member 6;130kDa pemphigus vulgaris antigen |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | DSG3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 3(981-999aa QLRGSHTMLCTEDPCSRLI). |
| 实际分子量 | 130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Desmoglein3 is also known as PVA(Pemphigus Vulgaris Antigen).Pemphigus vulgaris(PV) and pemphigus foliaceus(PF) are autoimmune diseases of the skin which have as target antigens 2 different members of the desmoglein subfamily of the desmosomal cadherins:pemphigus vulgaris antigen(PVA,or desmoglein-3) in the case of PV and desmoglein I in the case of PF.The DSG3 gene,like the genes for DSG1 and DSG2,is located on chromosome 18.The human DSG3 gene consists of 15 exons and spans more than 23kb.DSG3 and DSG1 are the autoantigens of pemphigus vulgaris and pemphigus foliaceus,respectively.DSG3 and DSG1 are the target antigens in PNP,and IgG autoantibodies against DSG3 in PNP sera play a pathogenic role in the loss of keratinocyte adhesion and blistering. |
| Uniprot ID | P32926 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | desmoglein 3 |
| 蛋白名全称 | Desmoglein-3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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