产品货号：
Z15943
中文名称：
DROSHA抗体
英文名称：
Anti-DROSHA Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DROSHA Antibody |
| 指标别名 | DROSHA;ETOHI2;HSA242976;p241;RANSE3L;Ribonuclease 3;Ribonuclease III;ribonuclease type III;nuclear;RN3;RNase III;RNASE3L;RNASEN |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | DROSHA |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human DROSHA recombinant protein (Position:E670-H903). |
| 实际分子量 | 159KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Drosha is a Class 2 ribonuclease III enzyme that in humans is encoded by the DROSHA (formerly RNASEN) gene.This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex,which catalyzes the initial processing step of microRNA (miRNA) synthesis.The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus,yielding the precursor miRNA (pre-miRNA),which is then exported to the cytoplasm for further processing.In a human cell line lacking a functional copy of this gene,canonical miRNA synthesis is reduced.Somatic mutations in this gene have been observed in human patients with kidney cancer. |
| Uniprot ID | Q9NRR4 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | drosha ribonuclease III |
| 蛋白名全称 | Ribonuclease 3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 ELISA 1:100～1000 Flow cytometry (FCM) 1～3μg/1×106 cells |
相关搜索：DROSHA抗体，DROSHA多抗，Anti-DROSHA Antibody