产品货号:
Z15850
中文名称:
DISP3/PTCHD2抗体
英文名称:
Anti-DISP3/PTCHD2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DISP3/PTCHD2 Antibody |
指标别名 | DISP3;DISP3;KIAA1337;Patched domain-containing protein 2;Protein dispatched homolog 3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,IHC |
基因名称 | PTCHD2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | PTCHD2 antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human PTCHD2.The immunogen is located within amino acids 1240 - 1290 of PTCHD2. |
计算分子量 | 153kDa |
成分 | PTCHD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | PTCHD2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | PTCHD2,also known as DISP3,is the third of three known homologs of the D.melanogaster protein Dispatched.It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins.Like DISP1 and DISP2,DISP3 has been implicated in signaling pathways during embryogenesis,tissue regeneration,and carcinogenesis.It is highly expressed in Purkinje cells,hippocampal neurons,and retinal ganglion cells.Recently,it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol,and given that its expression is regulated by thyroid hormone (T3),it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism. |
Uniprot ID | Q9P2K9 |
基因名全称 | Patched domain containing 2 |
蛋白名全称 | Patched domain containing 2 |
推荐稀释比 | PTCHD2 antibody can be used for detection of PTCHD2 by immunohistochemistry at 5μg/mL.Antibody validated:Immunohistochemistry in human samples.All other applications and species not yet tested. |
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