
产品货号:
Z15805
中文名称:
DCLK1抗体
英文名称:
Anti-DCLK1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DCLK1 Antibody |
指标别名 | DCAMKL1;DCDC3A;DCLK;DCLK1;doublecortin like kinase 1;KIAA0369 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | DCLK1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | DCLK1 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human DCLK1.The immunogen is located within the last 50 amino acids of DCLK1. |
计算分子量 | 82kDa |
成分 | DCLK1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | DCLK1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | DCLK1 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures. |
背景资料 | DCLK1 is one of three doublecortin-like kinases similar to the Ca2+/calmodulin-dependent protein kinase (CaMK) family.DCLK1 mRNA,like that of the homologous DCLK2 and DCLK3,is highly expressed in adult brain,but only DCLK1 and DCLK2 transcripts are present in human fetal brain and the developing mouse embryo,suggesting that DCLK1 and DCLK2 may play roles in cortical development.The DCLK proteins are homologous to Doublecortin (DCX),a gene that is mutated in X-linked human lissencephaly.In mouse models where the DCX gene has been disrupted,DCLK1 expression increases slightly and appears to compensate for the loss of DCX,as mice mutant for both DCX and DCLK1 show a severe phenotype including perinatal lethality,disorganized neocortical layering,and profound hippocampal cytoarchitectural disorganization.Unlike DCLK1,DCLK2 expression does not change in DCX-null mice. |
Uniprot ID | O15075 |
基因名全称 | Doublecortin-like kinase 1 |
蛋白名全称 | Doublecortin-like kinase 1 |
推荐稀释比 | DCLK1 antibody can be used for detection of DCLK1 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human and rat samples;Immunohistochemistry in mouse and rat samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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