产品货号：
Z15616
中文名称：
CPSF4抗体
英文名称：
Anti-CPSF4 antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CPSF4 antibody |
| 指标别名 | CPSF 30kDa subunit;CPSF30;CPSF4;NAR;Neb 1;NEB1;No arches homolog |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC,ICC/IF,IP,ELISA |
| 基因名称 | CPSF4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CPSF4 recombinant protein (Position:M1-F240). |
| 实际分子量 | 27～30KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain.The NS1 effector domain functionally interacts with the cellular 30kDa subunit of cleavage and polyadenylation specific factor 4,an essential component of the 3' end processing machinery of cellular pre-mRNAs.In influenza virus-infected cells,the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4,30kD subunit.Binding of the NS1 protein to the 30kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs.Thus the NS1 protein selectively inhibits the nuclear export of cellular,and not viral,mRNAs.Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. |
| Uniprot ID | O95639 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | cleavage and polyadenylation specific factor 4 |
| 蛋白名全称 | Cleavage and polyadenylation specificity factor subunit 4 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Enzyme linked immunosorbent assay (ELISA) 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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