产品货号：
Z15419
中文名称：
DR5/TNFRSF10B抗体
英文名称：
Anti-DR5/TNFRSF10B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DR5/TNFRSF10B Antibody |
| 指标别名 | CD262;Death receptor 5;DR5;KILLER;KILLER/DR5;TNFRSF10B;TRAIL R2;TRAIL receptor 2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | TNFRSF10B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human DR5(333-348aa DPTETLRQCFDDFADL). |
| 实际分子量 | 48KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | TNFRSF10B(Tumor necrosis factor receptor superfamily,member 10b) is a human gene.It is also known as DR5,CD262,KILLER,TRICK2,TRICKB,ZTNFR9,TRAILR2,TRICK2A,TRICK2B,TRAIL-R2,KILLER/DR5.The protein encoded by this gene is a member of the TNF-receptor superfamily,and contains an intracellular death domain.This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand(TNFSF10/TRAIL/APO-2L),and transduces apoptosis signal.Mice have a homologous gene,tnfrsf10b,that has been essential in the elucidation of the function of this gene in humans.Studies with FADD-deficient mice suggested that FADD,a death domain containing adaptor protein,is required for the apoptosis mediated by this protein.By analysis of radiation hybrid panels,Walczak et al.(1997) mapped the TRAILR2 gene to chromosome 8p22-p21.Northern blot analysis indicated that TRAILR2 was expressed as a 4.4-kb mRNA in all tissues tested,with the highest levels of expression in peripheral blood lymphocytes,spleen,and ovary. |
| Uniprot ID | O14763 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | tumor necrosis factor receptor superfamily,member 10b |
| 蛋白名全称 | Tumor necrosis factor receptor superfamily member 10B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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