DR5/TNFRSF10B抗体

产品货号：

Z15403

中文名称：

DR5/TNFRSF10B抗体

英文名称：

Anti-DR5/TNFRSF10B Antibody

产品规格：

0.1mg

发货周期：

1～3天

产品价格：

询价

抗体名称	Anti-DR5/TNFRSF10B Antibody
指标别名	CD262;Death receptor 5;DR5;KILLER;KILLER/DR5;TNFRSF10B;TRAIL R2;TRAIL receptor 2;TRAILR2;TRICK2;TRICK2A;TRICK2B;TRICKB;ZTNFR9
克隆性	Polyclonal
检验物种	human,mouse,rat
应用范围	ELISA,WB,IHC,IF
基因名称	TNFRSF10B
抗体来源	Rabbit
抗体类型	IgG
免疫原	DR5 antibody was raised against a peptide corresponding to 20 amino acids near the carboxy terminus of human DR5 precursor.The immunogen is located within the last 50 amino acids of DR5.
计算分子量	48kDa
成分	DR5 Antibody is supplied in PBS containing 0.02% sodium azide.
纯化方式	DR5 Antibody is affinity chromatography purified via peptide column.
浓度	1mg/mL
产品形态	溶液
保存条件	DR5 antibody can be stored at 4℃ up to one year.Antibodies should not be exposed to prolonged high temperatures.
背景资料	Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors.TRAIL/Apo2L is a new member of the TNF family.DR4 was recently identified as the receptor for TRAIL.A novel death domain containing receptor for TRAIL was more recently identified and designated DR5,Apo2,TRAIL-R2,TRICK2,or KILLER by several groups independently.Like DR4,DR5 transcript is widely expressed in normal tissues and in many types of tumor cells.DR5 binds to TRAIL and mediates TRAIL induced cell death.Overexpression of DR5 induces apoptosis and activates NF-百B.
Uniprot ID	O14763
基因名全称	Tumor necrosis factor receptor superfamily,member 10b
蛋白名全称	Tumor necrosis factor receptor superfamily,member 10b
推荐稀释比	WB:0.5～2μg/mL;IHC:5μg/mL;IF:5～10μg/mL.Antibody validated:Western Blot in human,mouse and rat samples;Immunohistochemistry in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human,mouse and rat samples.All other applications and species not yet tested.

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