产品货号：
Z15389
中文名称：
DYRK2抗体
英文名称：
Anti-DYRK2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DYRK2 Antibody |
| 指标别名 | Dual specificity tyrosine-phosphorylation-regulated kinase 2 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | DYRK2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DYRK2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human DYRK2.The immunogen is located within amino acids 520 - 570 of DYRK2. |
| 计算分子量 | 67kDa |
| 成分 | DYRK2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DYRK2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | DYRK2 is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family that is thought to be involved in cellular proliferation and apoptosis.Under normal conditions,nuclear but not cytoplasmic DYRK2 is ubiquitinated by MDM2,leading to its constitutive degradation.However,upon exposure to genotoxic stress,ATM phosphorylates DYRK2,leading to its dissociation from MDM2 and its phosphorylation of p53,thereby inducing apoptosis.Recent evidence also suggests that DYRK2 may serve as a scaffold that facilitates assembly of an E3 ubiquitin ligase. |
| Uniprot ID | Q92630 |
| 基因名全称 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| 蛋白名全称 | Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 |
| 推荐稀释比 | DYRK2 antibody can be used for detection of DYRK2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 10μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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