产品货号：
Z15306
中文名称：
CYP2E1抗体
英文名称：
Anti-CYP2E1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP2E1 Antibody |
| 指标别名 | 4 nitrophenol 2 hydroxylase;CPE1;CYP2E;CYP2E1;CYP-2E1;CYP2E1-Specific;CYPIIE1;Cytochrome P450 2E1;Cytochrome P450 J;P450 J;P450C2E |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | CYP2E1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Cytochrome P450 2E1/CYP2E1 recombinant protein (Position:H355-S493). |
| 实际分子量 | 57KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cytochrome P450 2E1 (abbreviated CYP2E1),a member of the cytochrome P450 mixed-function oxidase system,is involved in the metabolism of xenobiotics in the body.In humans,the CYP2E1 enzyme is encoded by the CYP2E1 gene.It is mapped to 10q26.3.While it is involved in the oxidative metabolism of a small range of substrates (mostly small polar molecules),there are many important drug interactions mediated by CYP2E1.Most drugs undergo deactivation by CYP2E1,either directly or by facilitated excretion from the body.Also,many substances are bioactivated by CYP2E1 to form their active compounds.In addition,CYP2E1 is an important enzyme for the conversion of ethanol to acetaldehyde and to acetate in humans.In the conversion sequence of acetyl-CoA to glucose,CYP2E1 transforms acetone via acetol into propylene glycol and methylglyoxal,the precursors of pyruvate,acetate and lactate. |
| Uniprot ID | P05181 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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