产品货号：
Z15183
中文名称：
CYP3A4抗体
英文名称：
Anti-CYP3A4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CYP3A4 Antibody |
| 指标别名 | Albendazole monooxygenase;Albendazole sulfoxidase;CP33;CP34;CYP3A;CYP3A11;CYP3A3;CYP3A4;CYPIIIA3;CYPIIIA4;Cytochrome P450 3A3;Cytochrome P450 3A4;Cytochrome P450 HLp;Cytochrome P450 NF 25;Cytochrome P450 PCN1;HLP;NF 25;Nifedipine oxidase;P450C3;P450PCN1;Quinine 3 monooxygenase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,FCM,ELISA |
| 基因名称 | CYP3A4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CYP3A4 recombinant protein (Position:L44-H267). |
| 实际分子量 | 50～57KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cytochrome P450 3A4 (abbreviated CYP3A4),is an important enzyme in the body,mainly found in the liver and in the intestine.This gene encodes a member of the cytochrome P450 superfamily of enzymes.The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol,steroids and other lipids.This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents.This enzyme is involved in the metabolism of approximately half the drugs in use today,including acetaminophen,codeine,cyclosporin A,diazepam and erythromycin.The enzyme also metabolizes some steroids and carcinogens.This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1.Previously another CYP3A gene,CYP3A3,was thought to exist;however,it is now thought that this sequence represents a transcript variant of CYP3A4.Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Uniprot ID | P08684 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | cytochrome P450 family 3 subfamily A member 4 |
| 蛋白名全称 | Cytochrome P450 3A4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 |
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