产品货号：
Z15121
中文名称：
E-cadherin/CDH1抗体
英文名称：
Anti-E-cadherin/CDH1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-E-cadherin/CDH1 Antibody |
| 指标别名 | Arc 1;Cadherin 1;CD324;CDH1;CDHE;E cadherin;ECAD;E-cad;E-cadherin;LCAM;UVO;Uvomorulin |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,IF,ICC/IF,IHC-F |
| 基因名称 | CDH1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human E Cadherin recombinant protein (Position:A286-A703).Human E Cadherin shares 79.7% and 80.9% amino acid (aa) sequence identity with mouse and rat E Cadherin,respectively. |
| 计算分子量 | 97KD |
| 实际分子量 | 130KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CDH1 (Cadherin 1),also known as ECAD or UVO,is a protein that in humans is encoded by the CDH1 gene.Cadherin-1 is a classical member of the cadherin superfamily.By Southern analysis of DNA from a panel of mouse-human somatic cell hybrids,Mansouri et al.(1987,1988) assigned the UVO gene to 16q (16p11-qter).Frebourg et al.(2006) found that in human embryos CDH1 is highly expressed at 4 and 5 weeks in the frontonasal prominence and at 6 weeks in the lateral and medial nasal prominences,and is therefore expressed during critical stages of lip and palate development.CDH1 is involved in mechanisms regulating cell-cell adhesions,mobility and proliferation of epithelial cells.Has a potent invasive suppressor role.It is a ligand for integrin alpha-E/beta-7. |
| Uniprot ID | P12830 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | cadherin 1,type 1,E-cadherin (epithelial) |
| 蛋白名全称 | Cadherin-1 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunohistochemistry in frozen section (IHC-F) 1:50～400 Immunofluorescence (IF) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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