产品货号：
Z14923
中文名称：
DEPDC6/DEPTOR抗体
英文名称：
Anti-DEPDC6/DEPTOR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DEPDC6/DEPTOR Antibody |
| 指标别名 | DEP domain containing 6,DEP.6,DEPDC6,Deptor |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC |
| 基因名称 | DEPTOR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | DEPTOR antibody was raised against a 16 amino acid peptide near the center of human DEPTOR.The immunogen is located within amino acids 220 - 270 of DEPTOR. |
| 计算分子量 | 46kDa |
| 成分 | DEPTOR Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | DEPTOR antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | DEPTOR is an mTOR (mammalian target of rapamycin)-interacting protein whose expression is negatively regualted by mTOR complex 1 (mTORC1) and mTORC2 (1).Loss of DEPTOR activates RP6SK1,Akt1,and SGK1,promotes cell growth and survival,and activates mTORC1 and mTORC2 kinase activities.DEPTOR expression is low in most cancers,but is often elevated in multiple myelomas (1).In respons to stimulation by mitogens,DEPTOR is rapidly phosphorylated leading to its ubiquitination and degradation,allowing mTOR to generate an auto-amplification loop to promotes its own full activation (2). |
| Uniprot ID | Q8TB45 |
| 基因名全称 | DEP domain containing MTOR-interacting protein |
| 蛋白名全称 | DEP domain containing MTOR-interacting protein |
| 推荐稀释比 | DEPTOR antibody can be used for detection of DEPTOR by Western blot at 1 ～ 2μg/mL.Antibody can also be used for Immunohistochemistry at 5μg/mL.Antibody validated:Western Blot in mouse samples and Immunohistochemistry in mouse samples.All other applications and species not yet tested. |
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