产品货号:
Z14914
中文名称:
DNASE2抗体
英文名称:
Anti-DNASE2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DNASE2 Antibody |
指标别名 | Acid DNase,Deoxyribonuclease 2 alpha,Deoxyribonuclease II alpha,DNase II alpha,DNASE2,DNASE2A,DNL,DNL2,Lysosomal DNase II,R31240_2 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | DNASE2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | DNase II antibody was raised against a 14 amino acid peptide near the carboxy terminus of human DNase II.The immunogen is located within the last 50 amino acids of DNase II. |
计算分子量 | 40kDa |
成分 | DNase II Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | DNase II Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is characterized by several morphological nuclear changes including chromatin condensation and nuclear fragmentation.These changes are triggered by the activation of members of caspase family,caspase activated DNase,and several novel proteins including AIF and Acinus.DNase II causes both chromatin condensation and DNA fragmentation.The genes encoding human,porcine,and murine DNase II have been cloned.The DNase II gene encodes a 40kDa proenzyme.The mature enzyme consists of two non-identical subunits,the 32kDa (alpha) and 12kDa (beta) chains,generated by proteolytic processing.Overexpression of DNase II induces chromatin condensation.DNase II is ubiquitously expressed in human tissues. |
Uniprot ID | O00115 |
基因名全称 | Deoxyribonuclease II,lysosomal |
蛋白名全称 | Deoxyribonuclease II,lysosomal |
推荐稀释比 | DNase II antibody can be used for detection of DNase II expression by Western blot at 0.5μg/mL.An approximate 40kDa band can be detected,which represents the pro-enzyme of DNase II.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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