产品货号：
Z14841
中文名称：
ER/ESR1抗体
英文名称：
Anti-ER/ESR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ER/ESR1 Antibody |
| 指标别名 | ER;ER alpha;Era;ERα;ESR;ESR1;ESRA;Estradiol receptor;Estrogen receptor;estrogen receptor 1;NR3A1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | ESR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Estrogen Receptor recombinant protein (Position:F425-V595).Human Estrogen Receptor shares 89% and 88% amino acid (aa) sequences identity with mouse and rat Estrogen Receptor,respectively. |
| 实际分子量 | 66KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Estrogen receptor alpha (ER-α),also known as NR3A1,is one of two main types of estrogen receptor,a nuclear receptor that is activated by the sex hormone estrogen.Estrogen receptors are involved in pathological processes including breast cancer,endometrial cancer,and osteoporosis.In humans,ER-α is encoded by the gene ESR1 (Estrogen Receptor 1).It is mapped to 6q25.1.This gene is a ligand-activated transcription factor composed of several domains important for hormone binding,DNA binding,and activation of transcription.The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2.Estrogen and its receptors are essential for sexual development and reproductive function,it also play a role in other tissues such as bone. |
| Uniprot ID | P03372 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | estrogen receptor 1 |
| 蛋白名全称 | Estrogen receptor |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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