产品货号:
Z14822
中文名称:
ER/ESR1抗体
英文名称:
Anti-ER/ESR1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ER/ESR1 Antibody |
指标别名 | ER;ER alpha;Era;ERα;ESR;ESR1;ESRA;Estradiol receptor;Estrogen receptor;estrogen receptor 1;NR3A1 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | ESR1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ESR1 antibody was raised against an 18 amino acid peptide near the center of human ESR1.The immunogen is located within amino acids 250 - 300 of ESR1. |
计算分子量 | 66kDa |
成分 | ESR1 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ESR1 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Estrogen receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors (1).Estrogen receptors,including ESR1,also known as ER-alpha and ESR2 (ER-beta),contain DNA binding and ligand binding domains and are critically involved in regulating the normal function of reproductive tissues.ESR1 is a widely expressed nuclear protein and serves as a strong activator of estrogen responsive genes (1,2).Phosphorylation of serines 104 and 106,located in the N-terminal transcription activation function-1 domain (AF-1),plays a large role in regulating ER alpha activity (3). |
Uniprot ID | P03372 |
基因名全称 | Estrogen receptor 1 |
蛋白名全称 | Estrogen receptor 1 |
推荐稀释比 | ESR1 antibody can be used for detection of ESR1 by Western blot at 1~2μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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