产品货号：
Z14785
中文名称：
FGF8抗体
英文名称：
Anti-FGF8 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FGF8 Antibody |
| 指标别名 | AIGF;Androgen induced growth factor;FGF 8;FGF8;Fibroblast growth factor 8;HBGF 8;KAL6 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ELISA |
| 基因名称 | FGF8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human FGF8 recombinant protein (Position:Q23-R233). |
| 实际分子量 | 26KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Fibroblast growth factor 8 (androgen-induced),also known as FGF8 or AIGF,is a human gene which maps to 10q24.The protein encoded by this gene is secreted proteins that interact with FGF tyrosine kinase receptors to mediate growth and development.This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells.Overexpression of this gene has been shown to increase tumor growth and angiogensis.The temporal and spatial patterns of this gene expression suggest that FGF8 is involved in gastrulation,regionalization of the brain,and organogenesis of the limb and face as an embryonic epithelial factor.The adult expression of FGF8 is restricted to gonads,including testes and ovaries.FGF8 stimulated growth of human prostate carcinoma cells and mouse fibroblasts and mammary carcinoma cells in a dose-dependent manner.It also may play an important role in growth and patterning of limbs,face,and central nervous system.FGF8 is expressed in increased levels in breast cancer and in lactating human breast;it was also detected in human milk.A survey of other normal tissues showed that FGF8 is expressed in the proliferative cells of the skin and epithelial cells in colon,ovary,fallopian tube,and uterus. |
| Uniprot ID | P55075 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 (ELISA)： 1:100～1000 |
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