产品货号:
Z14707
中文名称:
DAPK3抗体
英文名称:
Anti-DAPK3 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-DAPK3 Antibody |
指标别名 | DAP kinase 3;DAP like kinase;DAPK3;Dlk;phosphorylation ZIPK;Phospho-ZIPK (Ser311);ZIP;ZIP kinase;ZIPK |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | DAPK3 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | ZIP kinase antibody was raised against a peptide corresponding to amino acids near the center of human ZIP kinase.The immunogen is located within amino acids 270 - 320 of ZIPK. |
计算分子量 | 53kDa |
成分 | ZIPK Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | ZIPK Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis is mediated by death domain containing adapter molecules and a caspase family of proteases.Certain serine/threonine protein kinases,such as ASK-1 and RIP,are mediators of apoptosis.A novel serine/threonine kinase that mediates apoptosis was recently identified and designated ZIP kinase.ZIP kinase contains an N-terminal kinase domain and a C-terminal leucine zipper structure and binds to ATF4 that is a member of ATF/CREB family.ZIP kinase has high sequence homology to DAP kinase (death-associated protein kinase),which is a mediator of apoptosis induced by gamma interferon.Overexpression of ZIP kinase induces apoptosis.ZIP and DAP kinases represent a novel kinase family,which mediates apoptosis through their catalytic activities.The messenger RNA was ubiquitously expressed in various tissues. |
Uniprot ID | O43293 |
基因名全称 | Death-associated protein kinase 3 |
蛋白名全称 | Death-associated protein kinase 3 |
推荐稀释比 | ZIPK antibody can be used for detection of DNase II expression by Western blot at 1μg/mL.An approximate 40kDa band can be detected,which represents the pro-enzyme of DNase II.Antibody can also be used for immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 5μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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