产品货号：
Z14644
中文名称：
ERG抗体
英文名称：
Anti-ERG Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERG Antibody |
| 指标别名 | ERG;erg 3;p55;Transcriptional regulator ERG;Transforming protein ERG |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,ICC/IF,ELISA |
| 基因名称 | ERG |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human ERG recombinant protein (Position:E20-Q274). |
| 实际分子量 | 55KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ERG (ETS-related gene) is an oncogene.ERG is a member of the ETS (erythroblast transformation-specific) family of transcription factors.The ERG gene encodes for a protein,also called ERG,that functions as a transcriptional regulator.This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors.All members of this family are key regulators of embryonic development,cell proliferation,differentiation,angiogenesis,inflammation,and apoptosis.The protein encoded by this gene is mainly expressed in the nucleus.It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins.This protein is required for platelet adhesion to the subendothelium,inducing vascular cell remodeling.It also regulates hematopoesis,and the differentiation and maturation of megakaryocytic cells.This gene is involved in chromosomal translocations,resulting in different fusion gene products,such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer,EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia.More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported,but the full-length nature of many of these variants has not been determined. |
| Uniprot ID | P11308 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | ETS transcription factor ERG |
| 蛋白名全称 | Transcriptional regulator ERG |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ELISA 1:100～1000 |
相关搜索：ERG抗体，ERG多抗，Anti-ERG Antibody