产品货号：
Z14631
中文名称：
FAIM3/FCMR抗体
英文名称：
Anti-FAIM3/FCMR Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FAIM3/FCMR Antibody |
| 指标别名 | FCMR;TOSO;Fas apoptotic inhibitory molecule 3;Regulator of Fas-induced apoptosis Toso |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | FCMR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Toso antibody was raised against a 13 amino acid synthetic peptide from near the carboxy terminus of human Toso.The immunogen is located within the first 50 amino acids of Toso. |
| 计算分子量 | 43kDa |
| 成分 | Toso Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | Toso Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Apoptosis is an important process by which normal tissue homeostasis and function are maintained.One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand.This leads to the formation of a Fas-associated death domain (FADD)- containing death-inducing signaling complex and the activation of caspase-8,which in turn activates downstream effector caspases,such as caspase-3 and -7.Recent experiments have shown that overexpression of Toso,a novel regulator of Fas-induced apoptosis in lymphoid cells,in Jurkat cells as well as transgenic mice render these cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis.Furthermore,Toso was found to associate with FADD,suggesting that Toso functions by disrupting the formation of the death-inducing signaling complex. |
| Uniprot ID | O60667 |
| 基因名全称 | Fas apoptotic inhibitory molecule 3 |
| 蛋白名全称 | Fas apoptotic inhibitory molecule 3 |
| 推荐稀释比 | Toso antibody can be used for detection of Toso by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in human samples.All other applications and species not yet tested. |
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