产品货号:
Z14529
中文名称:
EPLIN/LIMA1抗体
英文名称:
Anti-EPLIN/LIMA1 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-EPLIN/LIMA1 Antibody |
指标别名 | EPLIN;LIM domain and actin binding 1;LIMA1;SREBP3 |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | LIMA1 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | LIMA1 antibody was raised against an 18 amino acid peptide near the amino terminus of human LIMA1.The immunogen is located within amino acids 230 - 280 of LIMA1. |
计算分子量 | 85kDa |
成分 | LIMA1 antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | LIMA1 antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The Lim domain and actin-binding protein 1 (LIMA1) is cytoskeleton-associated protein that inhibits actin filament depolymerization and cross-links filaments in bundles and is downregulated in some cancer cell lines (1,2).LIMA1 is also a key molecule linking the cadherin-catenin complex to the actin cytoskeleton (3).Recent studies have shown that EGF activates ERK1/2-dependent phosphorylation,ubiquitination and degradation of LIMA1,leading to increased invasiveness and metastasis of metastatic prostate cancer models (4). |
Uniprot ID | Q9UHB6 |
基因名全称 | LIM domain and actin binding 1 |
蛋白名全称 | LIM domain and actin binding 1 |
推荐稀释比 | LIMA1 antibody can be used for detection of LIMA1 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunohistochemistry starting at 5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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