产品货号：
Z14300
中文名称：
COX2/Cyclooxygenase 2/PTGS2抗体
英文名称：
Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody |
| 指标别名 | COX 2;COX2;COX2/Cyclooxygenase 2;COX2/Cyclooxygenase 2/PTGS2;Cyclooxygenase 2;GRIPGHS;hCox 2;PGG/HS;PGH synthase 2;PGHS 2;PHS 2;PHS II;Prostaglandin G/H synthase 2;Prostaglandin H2 synthase 2;PTGS2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse |
| 应用范围 | WB,IHC |
| 基因名称 | PTGS2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human COX2(589-604aa DDINPTVLLKERSTEL). |
| 实际分子量 | 75KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cyclooxygenase(Cox) is the key enzyme in conversion of arachidonic acid to PGs,and two isoforms,Cox-1 and Cox-2,have been identified.Cox-2 gene encodes an inducible prostaglandin synthase enzyme that is overexpressed in adenocarcinomas and other tumors.Deletion of the murine Cox-2 gene in Min mice reduced the incidence of intestinal tumors,suggesting that it is required for tumorigenesis.This gene is localized to sites associated with retinal blood vessels,and plays an important role in blood vessel formation in the retina.And the glucocorticoid receptor suppression of COX-2 is also crucial for curtailing lethal immune activation,and suggest new therapeutic approaches for regulation of T-cell-mediated inflammatory diseases. |
| Uniprot ID | P35354 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | prostaglandin-endoperoxide synthase 2(prostaglandin G/H synthase and cyclooxygenase) |
| 蛋白名全称 | Prostaglandin G/H synthase 2 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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