产品货号：
Z14199
中文名称：
COX-1/Cyclooxygenase-1/PTGS1抗体
英文名称：
Anti-COX-1/Cyclooxygenase-1/PTGS1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-COX-1/Cyclooxygenase-1/PTGS1 Antibody |
| 指标别名 | COX1;COX-1;COX-1/Cyclooxygenase-1;COX3;Cyclooxygenase 1;PCOX1;PGG/HS;PGH synthase 1;PGHS 1;PGHS1;PHS 1;PHS1;Prostaglandin G/H synthase 1;Prostaglandin H2 synthase 1;PTGHS;PTGS1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | PTGS1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human COX1(35-52aa CCYYPCQHQGICVRFGLD),different from the related rat and mouse sequences by two amino acids. |
| 实际分子量 | 70KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Cyclooxygenase 1(COX1),also known as Prostaglandin-endoperoxide synthase(PTGS1) or mitochondrial cytochrome c oxidase subunit 1,is the key enzyme in prostaglandin biosynthesis.The gene was approximately 40kb long,with 11 protein-coding exons.There were 599 amino acid residues with a calculated molecular mass of approximately 68kD.By analysis of a human/hamster somatic hybrid DNA panel,Funk et al.(1991) demonstrated that the PTGS1 gene maps to chromosome 9.Human prostaglandin endoperoxide synthase exhibited 91% amino acid identity with the sheep enzyme.Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration. |
| Uniprot ID | P23219 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1866) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | prostaglandin-endoperoxide synthase 1(prostaglandin G/H synthase and cyclooxygenase) |
| 蛋白名全称 | Prostaglandin G/H synthase 1 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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