产品货号：
Z14041
中文名称：
DICER1抗体
英文名称：
Anti-DICER1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-DICER1 Antibody |
| 指标别名 | DCR1;Dicer;dicer 1;ribonuclease type III;DICER1;Endoribonuclease Dicer;Helicase MOI;Helicase with RNase motif;HERNA;KIAA0928 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,FCM |
| 基因名称 | DICER1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Dicer recombinant protein (Position:M1-N195).Human Dicer shares 94% amino acid (aa) sequence identity with mouse Dicer. |
| 实际分子量 | 250KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Dicer(DICER1),also known as endoribonuclease Dicer or helicase with RNase motif,is an enzyme that in humans is encoded by the DICER1 gene.It is mapped to 14q32.13.The DICER1 gene,a member of the ribonuclease III (RNaseIII) family,is involved in the generation of microRNAs (miRNAs),which modulate gene expression at the posttranscriptional level.DICER1 possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus DICER,also known as helicase-MOI,is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression.In addition,DICER1 is required for formation of the RNA induced silencing complex (RISC).It also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. |
| Uniprot ID | Q9UPY3 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | dicer 1,ribonuclease type III |
| 蛋白名全称 | Endoribonuclease Dicer |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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