产品货号：
Z13919
中文名称：
Decorin/DCN抗体
英文名称：
Anti-Decorin/DCN Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Decorin/DCN Antibody |
| 指标别名 | Bone proteoglycan II;CSCD;DCN;Decorin;DSPG2;PG S2;PG40;PGII;PGS2;SLRR1B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rabbit,rat |
| 应用范围 | WB,IHC |
| 基因名称 | DCN |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human Decorin(343-359aa TFRCVYVRSAIQLGNYK),identical to the related mouse sequence,and different from the related rat sequence by three amino acids. |
| 实际分子量 | 40KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Decorin is a proteoglycan on average 90-140 kilodaltons(kD) in size.The human decorin gene spans more than 38kb and contains 8 exons and very large introns,2 of which are 5.4 and more than 13.2kb.And the human decorin gene is mapped to 12q21.3.It belongs to the small leucine-rich proteoglycan(SLRP) family and consists of a protein core containing leucine repeats with a glycosaminoglycan(GAG) chain consisting of either chondroitin sulfate(CS) or dermatan sulfate(DS).Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein.Decorin and biglycan are though to be the result of a gene duplication.This protein is a component of connective tissue,binds to type I collagen fibrils,and plays a role in matrix assembly.And it also may play a role in epithelial/mesenchymal interactions during organ development and shaping.Decorin has been shown to have anti-tumorigenic properties in an experimental murine tumor model and is capable of suppressing the growth of various tumor cell lines.There are multiple alternatively spliced transcript variants known for the decorin gene.Mutations in the decorin gene are associated with congenital stromal corneal dystrophy. |
| Uniprot ID | P07585 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | decorin |
| 蛋白名全称 | Decorin |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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