产品货号：
Z13805
中文名称：
CXCL1抗体
英文名称：
Anti-CXCL1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CXCL1 Antibody |
| 指标别名 | CXCL1;GRO;GRO1;GROA;MGSA;SCYB1;Growth-regulated alpha protein;C-X-C motif chemokine 1;GRO-alpha(1-73);Melanoma growth stimulatory activity;MGSA;Neutrophil-activating protein 3;NAP-3 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | IHC,Direct ELISA |
| 基因名称 | CXCL1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CXCL1 recombinant protein (Position:A35-N107). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | CXCL1(Chemokine,CXC motif,Ligand 1),also called GRO1,SCYB1,GROA or MGSA,is a small cytokine belonging to the CXC chemokine family that was previously called GRO1 oncogene,GROalpha,KC,Neutrophil-activating protein 3(NAP-3) and melanoma growth stimulating activity,alpha(MSGA-alpha).In humans,this protein is encoded by the CXCL1 gene.The CXCL1 gene is mapped on 4q13.3.CXCL1 is secreted by human melanoma cells,has mitogenic properties and is implicated in melanoma pathogenesis.CXCL1 is expressed by macrophages,neutrophils and epithelial cells,and has neutrophil chemoattractant activity.CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis,inflammation,wound healing,and tumorigenesis.Signaling through Cxcr2,Cxcl1 inhibited oligodendrocyte precursor migration.The migrational arrest was rapid,reversible,and concentration dependent,and it reflected enhanced cell/substrate interactions.White matter expression of Cxcl1 was temporospatially regulated.Others contribute to aggressive growth selectivity in the lung.Among the lung metastasis signature genes identified,several,including CXCL1,were functionally validated. |
| Uniprot ID | P09341 |
| 推荐配套试剂 | Biorab recommends HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P). |
| 基因名全称 | C-X-C motif chemokine ligand 1 |
| 蛋白名全称 | Growth-regulated alpha protein |
| 推荐稀释比 | Immunohistochemistry in paraffin section (IHC) 1:50～400 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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