产品货号：
Z13764
中文名称：
CTCFL抗体
英文名称：
Anti-CTCFL Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CTCFL Antibody |
| 指标别名 | BORIS;Cancer/testis antigen 27;CCCTC binding factor;CT27;CTCF like protein;CTCF paralog;CTCF T;CTCFL;Zinc finger protein CTCF T |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | CTCFL |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to N-Terminal region near aa 1-30 of human BORIS protein. |
| 计算分子量 | 76kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity-purified antibody is directed against the human BORIS protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest cross-reactivity with BORIS proteins from human and chimpanzee.Partial reactivity may occur against BORIS from mouse,dog and rat sources based on varying degrees of homology to the immunizing sequence.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.28mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store BORIS Antibody at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | Anti-BORIS antibody is suitable for Cancer,Immunology and Nuclear Signaling research.BORIS (Brother of the Regulator of Imprinted Sites) also known as CCCTC-binding factor-like protein,is normally only expressed in the testis and expressed in a mutually exclusive manner with CTCF during male germ cell development.However,previous studies have shown that BORIS is abnormally activated in a wide range of human cancers.Expression of BORIS in normally BORIS-negative cells promotes cell growth that may lead to transformation.BORIS maps to the cancer-associated amplification region thought to contain an oncogene or dominant-immortalizing gene.BORIS is a candidate protein for the epigenetic reprogramming factor acting in the male germ line.BORIS is found in both the nucleus and cytoplasm.BORIS antibody can be used to investigate epigenetic regulation. |
| Uniprot ID | Q8NI51 |
| 基因名全称 | Transcriptional repressor CTCFL |
| 推荐稀释比 | ELISA:1:2,000 - 1:10,000 WB:1:200 - 1:2,000 |
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