产品货号：
Z13430
中文名称：
CDCA8抗体
英文名称：
Anti-CDCA8 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CDCA8 Antibody |
| 指标别名 | BOR;BOREALIN;CDCA8;Dasra B;hDasra B;PESCRG3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IF |
| 基因名称 | CDCA8 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | CDCA8 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of the human CDCA8.The immunogen is located within the first 50 amino acids of CDCA8. |
| 计算分子量 | 31kDa |
| 成分 | CDCA8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | CDCA8 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | CDCA8 is a component of a chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle.The chromosomal passenger complex,which includes Survivin,CDCA8,INCENP and Aurora-B,is known to play crucial roles during mitosis and cell division.It was found that CDCA8 interacting with Aurora-B,INCENP and Survivin,increases during G2/M phase and then reduces after exit from M phase.CDCA8 is cell cycle regulated,down-regulated in response to p53/Rb-signaling,and up-regulated in many types of cancerous tissues.In Drosophila cells,inactivation of CDCA8 results in polyploidy,delayed mitosis and abnormal tissue development,indicating its critical role for cell proliferation.Recent studies show that CDCA8 is essential for cell proliferation during early embryonic development,and its early embryonic lethality cannot be rescued by the loss of p53.Its aberrant expression is linked to a poor prognosis for gastric cancer. |
| Uniprot ID | Q53HL2 |
| 基因名全称 | Cell division cycle associated 8 |
| 蛋白名全称 | Cell division cycle associated 8 |
| 推荐稀释比 | CDCA8 antibody can be used for detection of CDCA8 by Western blot at 1 and 2μg/mL.Antibody can also be used for immunoflourescence starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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