
产品货号:
Z13356
中文名称:
CISD2抗体
英文名称:
Anti-CISD2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CISD2 Antibody |
指标别名 | CDGSH iron sulfur domain 2;CDGSH2;CISD2;ERIS;Miner1;MitoNEET related 1 protein;NAF 1;WFS2;ZCD2 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | CISD2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2.The immunogen is located within amino acids 40 - 90 of CISD2. |
计算分子量 | 15kDa |
成分 | CISD2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CISD2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Defects in the CISD2 (CDGSH iron sulfur domain 2) gene are a cause of the neurodegenerative disorder Wolfram syndrome 2.CISD2 is a zinc finger protein that localizes to the endoplasmic reticulum and mitochondria and binds an iron/sulfur cluster.CISD2 interacts with Bcl-2 and can be displaced by the BH3-only protein BIK and contributes to the regulation of BIK-initiated autophagy.CISD2 deficiency in mice causes mitochondrial breakdown accompanied by autophagic cell death as well as the development of premature aging phenotype. |
Uniprot ID | Q8N5K1 |
基因名全称 | CDGSH iron sulfur domain 2 |
蛋白名全称 | CDGSH iron sulfur domain 2 |
推荐稀释比 | CISD2 antibody was raised against a 15 amino acid peptide near the center of human CISD2.Antibody validated:Western Blot in rat samples;Immunohistochemistry in rat samples and Immunofluorescence in rat samples.All other applications and species not yet tested. |
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