产品货号:
Z13347
中文名称:
CITED2抗体
英文名称:
Anti-CITED2 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CITED2 Antibody |
指标别名 | CITED2;MRG 1;MRG1;MSG related protein 1;P35SRJ |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,IF |
基因名称 | CITED2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | CITED2 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human CITED2.The immunogen is located within the first 50 amino acids of CITED2. |
计算分子量 | 28kDa |
成分 | CITED2 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | CITED2 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | CITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1,a melanocyte-specific nuclear protein.CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2.CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf.CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs),with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs,multilineage bone marrow failure and increased lethality. |
Uniprot ID | Q99967 |
基因名全称 | Cbp/p300-interacting transactivator,with Glu/Asp-rich carboxy-terminal domain,2 |
蛋白名全称 | Cbp/p300-interacting transactivator,with Glu/Asp-rich carboxy-terminal domain,2 |
推荐稀释比 | CITED2 antibody can be used for detection of CITED2 by Western blot at 1 ~ 2μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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