产品货号：
Z13284
中文名称：
Cleaved-NOTCH2 (D1733)抗体
英文名称：
Anti-Cleaved-NOTCH2 (D1733) Antibody
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Cleaved-NOTCH2 (D1733) Antibody |
| 指标别名 | AGS2;hN2;Notch 2;Notch homolog 2 (Drosophila);NOTCH2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | NOTCH2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Synthesized peptide derived from human Notch 2 |
| 计算分子量 | 265KD |
| 成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| 纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | Neurogenic locus notch homolog protein 2 also known as notch 2 is a protein that in humans is encoded by the NOTCH2 gene.It is mapped to 1p12.This gene encodes a member of the Notch family.Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats,and an intracellular domain consisting of multiple,different domain types.Notch family members play a role in a variety of developmental processes by controlling cell fate decisions.The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells.In Drosophilia,notch interaction with its cell-bound ligands (delta,serrate) establishes an intercellular signaling pathway that plays a key role in development.Homologues of the notch-ligands have also been identified in human,but precise interactions between these ligands and the human notch homologues remain to be determined.This protein is cleaved in the trans-Golgi network,and presented on the cell surface as a heterodimer.This protein functions as a receptor for membrane bound ligands,and may play a role in vascular,renal and hepatic development.Two transcript variants encoding different isoforms have been found for this gene. |
| Uniprot ID | Q04721 |
| 基因名全称 | Neurogenic locus notch homolog protein 2 |
| 蛋白名全称 | Neurogenic locus notch homolog protein 2 |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:100～1:300 ELISA 1:40000 |
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