产品货号：
Z13274
中文名称：
Claudin 3/CLDN3抗体
英文名称：
Anti-Claudin 3/CLDN3 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Claudin 3/CLDN3 Antibody |
| 指标别名 | C7orf1;claudin 3;Claudin3;CLDN3;CPE R 2;CPE R2;CPE receptor 2;CPETR2;HRVP1;RVP1 |
| 克隆性 | Polyclonal |
| 检验物种 | mouse,rat |
| 应用范围 | WB,ICC/IF |
| 基因名称 | CLDN3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence of mouse Claudin 3/CLDN3 (RDKYAPTKILYSAPRST). |
| 实际分子量 | 20KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Claudin 3,also known as CLDN3,is a protein which in humans is encoded by the CLDN3 gene.This gene encodes a member of the claudin family.Claudins are integral membrane proteins and components of tight junction strands.Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets,and also play critical roles in maintaining cell polarity and signal transductions.The protein encoded by this gene is a low-affinity receptor for clostridium perfringens enterotoxin (CPE) produced by the bacterium Clostridium perfringens,and the interaction with CPE results in increased membrane permeability by forming small pores in plasma membrane.This protein is highly overexpressed in uterine carcinosarcoma.This protein is also predominantly present in brain endothelial cells,where it plays a specific role in the establishment and maintenance of blood brain barrier tight junction morphology. |
| Uniprot ID | Q9Z0G9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot. |
| 基因名全称 | claudin 3 |
| 蛋白名全称 | Claudin-3 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 |
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