产品货号：
Z13247
中文名称：
CD35/CR1抗体
英文名称：
Anti-CD35/CR1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-CD35/CR1 Antibody |
| 指标别名 | C3b/C4b receptor;C3BR;CD35;Complement receptor type 1;CR1;KN |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | CR1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human CD35/CR1 recombinant protein (Position:D109-Q957). |
| 实际分子量 | 224～300KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene.This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1.The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes,leukocytes,glomerular podocytes,and splenic follicular dendritic cells.The Knops blood group system is a system of antigens located on this protein.The protein mediates cellular binding to particles and immune complexes that have activated complement.Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas,mesangiocapillary glomerulonephritis,systemic lupus erythematosus and sarcoidosis.Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting,conferring protection against severe malaria.Alternate allele-specific splice variants,encoding different isoforms,have been characterized.Additional allele specific isoforms,including a secreted form,have been described but have not been fully characterized. |
| Uniprot ID | P17927 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (ELISA)： 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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