产品货号:
Z13246
中文名称:
CD35/CR1抗体
英文名称:
Anti-CD35/CR1 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD35/CR1 Antibody |
指标别名 | C3b/C4b receptor;C3BR;CD35;Complement receptor type 1;CR1;KN |
克隆性 | Polyclonal |
检验物种 | human |
应用范围 | WB |
基因名称 | CR1 |
抗体来源 | Rabbit |
免疫原 | Synthesized peptide derived from CD35 at AA range:Internal. |
计算分子量 | 224KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | Immunogen affinity purified |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Complement receptor type 1 (CR1) also known as C3b/C4b receptor or CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene.This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1.The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes,leukocytes,glomerular podocytes,and splenic follicular dendritic cells.The Knops blood group system is a system of antigens located on this protein.The protein mediates cellular binding to particles and immune complexes that have activated complement.Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas,mesangiocapillary glomerulonephritis,systemic lupus erythematosus and sarcoidosis.Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting,conferring protection against severe malaria.Alternate allele-specific splice variants,encoding different isoforms,have been characterized.Additional allele specific isoforms,including a secreted form,have been described but have not been fully characterized. |
Uniprot ID | P17927 |
基因名全称 | Complement receptor type 1 |
推荐稀释比 | WB,1:500~2000 |
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